Some of it, yes. Clearing the sensor lenses of dust or cobwebs, checking that the wall button and remote batteries are good, and resetting the opener's travel limits through the learn button are all things an owner can do with the manual in hand. If the door reverses randomly or won't close, start there before you call anyone. What you shouldn't take on yourself: anything involving the torsion spring system above the door, or pulling the opener head down while the door is under tension from a bad spring. Those two problems get confused for opener trouble more than you'd expect - a dying spring makes the opener strain and sometimes trip its own safety cutoff, which looks exactly like an opener fault but isn't one. If the door feels heavy when you lift it by hand with the opener disconnected, that's a spring problem, not an opener problem, and it's not a DIY repair.